CELEBREX 200MG CAPSULE contains Celecoxib which belongs to group of medicines called Non-steroidal anti-inflammatory drugs. CELEBREX 200MG CAPSULE is used in adults to manage osteoarthritis (degenerative joint disease), rheumatoid arthritis (inflammatory disease of joints), ankylosing spondylitis (chronic back pain), acute pain and primary dysmenorrhea (menstrual cramps).
CELEBREX 200MG CAPSULE is also used to manage juvenile rheumatoid arthritis (in children aged 2 years and above).
CELEBREX 200MG CAPSULE is not recommended for use in patients allergic to Celecoxib, sulfonamides, aspirin and/or other NSAIDs. It is also not recommended for use in patients with/had a history of an ulcer in stomach/intestines, bleeding in stomach/intestines, blood circulation problems (such as peripheral arterial disease), red itchy welts, inflammatory disease of the intestines (such as ulcerative colitis/Crohn’s disease).
The medicine is also not indicted for use in patients suffering from lung problems (such as asthma), heart diseases (such as heart failure, recent heart attack, heart block), severe liver disease (such as advanced hepatic insufficiency) and/or kidney disease (such as advanced renal insufficiency).
Before taking CELEBREX 200MG CAPSULE, inform your doctor if you have diabetes, raised blood pressure, increased cholesterol, signs of fluid retention (such as swollen ankles and feet) and/or hyperkalemia (increased potassium level in blood).
CELEBREX 200MG CAPSULE is not recommended for use in pregnant and breast-feeding women.
CELEBREX 200MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) to manage only juvenile rheumatoid arthritis and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking CELEBREX 200MG CAPSULE are high blood pressure, shortness of breath, sore throat, cough, headache, nausea and dizziness. Consult your doctor if any of these symptoms worsen.
ReferencesSide effectsIn clinical trials, 100 mg of CELEBREX 200MG CAPSULE was found to be more effective in treating osteoarthritis symptoms than 200 mg of Celebrex 100mg. The combination of the two medicines led to an average increase of 24.2% in the reduction of pain, 13.1% increase in the increase in swelling and 1.6% increase in the decrease in swelling over one month. The median pain score was reduced by 1.5 points (95% CI, (0.8 to 3.1), p=0.14).
Higher doses (200 mg) also seem to be more effective in reducing pain, swelling and pain compared to lower doses (100 mg).
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A recent study suggests that the COX-2 inhibitor celecoxib may have a beneficial effect in the treatment of patients with non-steroidal anti-inflammatory drugs (NSAIDs) who have developed gastrointestinal bleeding.
The study, published in, examined the efficacy of celecoxib (Celebrex) in patients with non-steroidal anti-inflammatory drug (NSAID) ulcers and found that patients on celecoxib experienced significantly better rates of ulcer healing compared to those on placebo.
In contrast, the study was limited by a small number of patients, which may limit the strength of the findings.
The study was a randomized, double-blind, controlled trial, the findings of which are published in the journal.
"Our findings raise questions," said Dr. R. G. Dixit, a postdoctoral scholar at the Department of Gastroenterology, and an associate professor in the department of medicine at the University of Texas Health Science Center at Galveston.
The study was conducted in three phases of the COX-2 inhibitor treatment for non-steroidal anti-inflammatory drugs (NSAIDs) ulcers: phase I, phase II, and phase III, according to the National Institutes of Health.
The COX-2 inhibitor was approved in 2005 for the treatment of ulcer healing in patients who have had one or more of the following conditions:
The COX-2 inhibitor was studied for three time periods: pre-treatment, 1 year, and 3 months.
During the 1-year study period, patients were randomized to receive celecoxib (200 mg twice daily) or placebo. Patients were randomly assigned to receive either celecoxib or placebo. Patients on celecoxib had a significantly lower rate of ulcer healing compared to patients on placebo (p < 0.05).
Adverse events and safety profile of celecoxib are not known. In addition, patients were excluded from the trial if they had a history of gastrointestinal bleeding, gastrointestinal hemorrhage, bleeding between meals, or had any of the following conditions:
In phase II, celecoxib was also studied for patients with NSAID ulcers.
During the first 2 months of the study period, patients were randomized to receive celecoxib or placebo. Patients were randomly assigned to receive celecoxib or placebo. The celecoxib group had a lower rate of ulcer healing compared to the placebo group (p = 0.03).
In phase III, celecoxib was studied for all ulcer stages. During the 2-year study period, patients were randomized to receive celecoxib or placebo. Patients were randomly assigned to celecoxib or placebo.
The celecoxib group had a significantly lower rate of ulcer healing compared to the placebo group (p = 0.04).
In the first 2 months of the study period, celecoxib was compared with placebo in the patients who were randomized to receive celecoxib. The celecoxib group had a lower rate of ulcer healing compared to the placebo group (p = 0.01).
In phase III, celecoxib was compared with celecoxib in patients with a history of gastrointestinal bleeding. During the first 2-year study period, celecoxib was compared with placebo in the patients who were randomized to receive celecoxib.
Treatment of NSAIDs in ulcer healingTreatment of NSAIDs in NSAID ulcers
In NSAID ulcers, the treatment of choice is a daily dose of NSAIDs that provides symptom relief for several days, although patients should not take more than the recommended dose of aspirin.
Celebrex 100mg Tablet is used to treat pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. It helps reduce the pain associated with surgery or radiographic correction. It is also used to treat pain in children with non-arthritis of the back, buttocks, thighs, or thighs. It is used to relieve the pain of pain in patients with muscle-related conditions such as sprains, strains, or arthritis. You may ask questions like how many joints do I have, how many times do I have to have surgery, what's the muscle tone, what's stiffness, what's pain, what's pain force, how much pressure does it make, how many times do I have to have a sexual encounter, how many times have I had to have sex, how many have you had to have sex, how many have you had to have sex with, how many have I had to have sex with, how many have you had to have sex with, how many have I had to have sex with, how many have I had to have sex with. It can be taken with or without food. Do not take Celebrex 100mg Tablet for more than 10 days.
Take the tablet 1 day before planned activities or activity dates, as directed by your doctor. Drink a full glass of water with the tablet to prevent nausea. The dosage and length of treatment may vary depending on the severity and nature of the pain. You may experience muscle aches, joint pain, or weakness that bothers you or that does not interfere with daily life. If you find that the pain persists or improves, tell your doctor or pharmacist. Do not change your dose without consulting your doctor.
Treatment of osteoarthritis and other rheumatoid arthritis pain:
Treatment of dysmenorrhea pain:
Treatment of pain in dysmenorrhea:
Reduces the duration of pain in osteoarthritis and arthritis
The recommended dose of Celebrex 100mg Tablet for osteoarthritis and rheumatoid arthritis pain is one tablet (100 mg) 3 times a day. Do not exceed the recommended dose.
Store at room temperature (20-25°C/59- 86°F). Keep out of reach of children.
Celebrex 100mg Tablet may cause a moderate to severe increase in blood pressure, especially in patients who are taking other drugs to treat hypertension (high blood pressure). Patients taking other drugs that contain furosemide (fluconazole), ritonavir (Norvir), and tipranavir (Anvir) may also experience a severe hypertension-related reaction. It is important to tell your doctor about all the medications you are taking, including over-the-counter medicines, vitamins, minerals, and herbal products. Do not start a new medication without first consulting your healthcare provider.
Celebrex 100mg Tablet,Prescription only medicine used to treat pain and inflammation in osteoarthritis, rheumatoid arthritis, and dysmenorrhea.The dosage of Celebrex 100mg Tablet depends on the condition being treated and your age. The maximum recommended dose is one tablet (200 mg) 3 times a day.
Celebrex 100mg Tablet (Cocaine),Drug maker Pfizer Inc. is seeking the approval of an arthritis pain medicine, Celebrex, over the counter. The drug is called Bextra, or Coxib. It is available as a pill and as an oral tablet.
Pfizer Inc. is conducting a Phase 2 clinical study of Bextra for osteoarthritis patients who have not received the drug since Jan. 1, 1999. The study has not been approved.
Celebrex is approved by the U. S. Food and Drug Administration.
Pfizer is expected to offer the drug to more than 1,000 patients.
The FDA approved Celebrex for the following indications:
Patients with severe osteoarthritis may require a reduced dosage or treatment with a higher dose of the drug.
The drug is available without a prescription.
The Food and Drug Administration has not approved the use of Bextra in osteoarthritis patients with a contraindication to the drug.
Celebrex is used to treat a condition called rheumatoid arthritis that is caused by an inflamed joint in the spine or hips. Celebrex is also used to reduce the risk of developing osteoarthritis.
The drug is currently under review for approval by the FDA.
The FDA also has not been cleared for approval.
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Product information last updated2021.
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